On diet only

1. Evaluation of the Metabolic Effects of Excenetide, Rosiglitazone, and Excenatide Plus Rosiglitazone in Subjects with Type 2 Diabetes Mellitus Treated with Metformin. IRB#056-5014-092. Principal Investigator: Ralph De Fronzo, MD - (210) 358-7200.
   
   
2. Effect of Exenatide Treatment on Splanchnic Glucose Uptake in Patients with Type 2 Diabetes Mellitus. IRB# 045-5014-041. Principal Investigator: Ralph A DeFronzo, MD-(210) 358-7200.
   
   
3. Molecular Mechanisms of Inflammation-Associated Skeletal Muscle Insulin Resistance in Mexican Americans with Type 2 Diabetes. IRB# 045-5014-114. Principal Investigator: Nicolas Musi, MD-(210) 358-7200.

On oral medications

1. Anti-inflammatory Effect of Exercise in Skeletal Muscle: Novel Mechanism to Treat Insulin Resistance. IRB# HSC20060025H. Principal Investigator: Nicolas Musi, MD - (210) 358-7200.
   
   
2. Role of TLR4 on Insulin Resistance in Human Muscle. IRB# HSC20080015H. Principal Investigator: Nicolas Musi (210)358-7200
   
   
3. Molecular Mechanisms of Inflammation-Associated Skeletal Muscle Insulin Resistance in Mexican Americans with Type 2 Diabetes. IRB# 045-5014-114. Principal Investigator: Nicolas Musi, MD-(210) 358-7200.

On insulin therapy

• No studies at this time, please check back later.

On combination oral/insulin

1. Study of the Improvement of Metabolic Control, Insulin Resistance, Vascular Endothelial Dysfunction and Inflammation in Mexican American Type 2 Diabetic Patients Treated with Basal-Bolus Insulin Glargine-Apidra Comination. IRB# 056-5014-121. Principal Investigator: Eugenio Cersosimo, MD-(210) 358-7200.

Exercise

1. Anti-inflammatory Effect of Exercise in Skeletal Muscle: Novel Mechanism to Treat Insulin Resistance. IRB# 056-5014-025 Principal Investigator: Dr. Nicolas Musi-(210) 358-7200.

2. Molecular Mechanisms of Inflammation-Associated Skeletal Muscle Insulin Resistance in Mexican Americans with Type 2 Diabetes. IRB# 045-5014-114. Principal Investigator: Nicolas Musi, MD-(210) 358-7200.